B vitamins are a family of water-soluble nutrients, each with a distinct role to play in promoting health. B vitamins play critical roles in modulating biochemistry and metabolism, and represent the most common vitamins utilized by the body as cofactors for facilitating enzymatic function. The modern refined diet, high in sugar, alcohol, and devitalized foods, leads to lower levels of B vitamins. Stress and many medications may also lower B vitamin levels. While B vitamins have mainly been researched individually, they also have therapeutic power when taken together.